Impairment of Mitochondrial Redox Status in Peripheral Lymphocytes of Multiple Sclerosis Patients

Impairment of Mitochondrial Redox Status in Peripheral Lymphocytes of Multiple Sclerosis Patients

Literature suggests that oxidative stress (OS) may be involved in the pathogenesis of multiple sclerosis (MS), in which the immune system is known to play a key role. However, to date, the OS in peripheral lymphocytes and its contribution to the disease remain unknown. The aim of the present study w...

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Bibliographic Details
Main Authors: Hugo Gonzalo, Lara Nogueras, Anna Gil-Sánchez, José Vicente Hervás, Petya Valcheva, Cristina González-Mingot, Meritxell Martin-Gari, Marc Canudes, Silvia Peralta, Maria José Solana, Reinald Pamplona, Manuel Portero-Otin, Jordi Boada, Jose Carlos Enrique Serrano, Luis Brieva
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Neuroscience
Subjects:
multiple sclerosis
oxidative stress
mitochondria
superoxide anion
mitochondrial complexes
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00938/full

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https://www.frontiersin.org/article/10.3389/fnins.2019.00938/full

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