Gene Set Enrichment Analysis Reveals Individual Variability in Host Responses in Tuberculosis Patients

Gene Set Enrichment Analysis Reveals Individual Variability in Host Responses in Tuberculosis Patients

Group-aggregated responses to tuberculosis (TB) have been well characterized on a molecular level. However, human beings differ and individual responses to infection vary. We have combined a novel approach to individual gene set analysis (GSA) with the clustering of transcriptomic profiles of TB pat...

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Bibliographic Details
Main Authors: Teresa Domaszewska, Joanna Zyla, Raik Otto, Stefan H. E. Kaufmann, January Weiner
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
tuberculosis
endotypes
individual variability in host response
interferon
immune response
gene set enrichment analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.694680/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.694680/full

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