RECQ1 Helicase Silencing Decreases the Tumour Growth Rate of U87 Glioblastoma Cell Xenografts in Zebrafish Embryos

RECQ1 Helicase Silencing Decreases the Tumour Growth Rate of U87 Glioblastoma Cell Xenografts in Zebrafish Embryos

RECQ1 helicase has multiple roles in DNA replication, including restoration of the replication fork and DNA repair, and plays an important role in tumour progression. Its expression is highly elevated in glioblastoma as compared to healthy brain tissue. We studied the effects of small hairpin RNA (s...

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Bibliographic Details
Main Authors: Miloš Vittori, Barbara Breznik, Katja Hrovat, Saša Kenig, Tamara T. Lah
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Genes
Subjects:
cancer
cell cycle
DNA damage
intravital imaging
RNA interference
theranostics
Online Access:https://www.mdpi.com/2073-4425/8/9/222

Internet

https://www.mdpi.com/2073-4425/8/9/222

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