Genetic and molecular functional characterization of variants within TNFSF13B, a positional candidate preeclampsia susceptibility gene on 13q.

Genetic and molecular functional characterization of variants within TNFSF13B, a positional candidate preeclampsia susceptibility gene on 13q.

Preeclampsia is a serious pregnancy complication, demonstrating a complex pattern of inheritance. The elucidation of genetic liability to preeclampsia remains a major challenge in obstetric medicine. We have adopted a positional cloning approach to identify maternal genetic components, with linkages...

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Bibliographic Details
Main Authors: Mona H Fenstad, Matthew P Johnson, Linda T Roten, Per A Aas, Siri Forsmo, Kjetil Klepper, Christine E East, Lawrence J Abraham, John Blangero, Shaun P Brennecke, Rigmor Austgulen, Eric K Moses
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2947510?pdf=render

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http://europepmc.org/articles/PMC2947510?pdf=render

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