A negative Smad2/miR-9/ANO1 regulatory loop is responsible for LPS-induced sepsis

The roles of miR-9 in tumor progression are well-defined, however, its roles and the mechanisms in sepsis are still unclear. This work aims to explore miR-9 roles and related mechanism in LPS-induced sepsis. We found that miR-9 level was significantly upregulated in septic patients and RAW264.7 cell...

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Bibliographic Details
Main Authors: Jie Zhen, Wei Chen, Lei Zhao, Xuefeng Zang, Yang Liu
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Biomedicine & Pharmacotherapy
Subjects:
LPS
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219314258