Therapeutic Efficacy of a Novel Acetylated Tetrapeptide in Animal Models of Age-Related Macular Degeneration
It has been shown previously that a novel tetrapeptide, Arg-Leu-Tyr-Glu (RLYE), derived from human plasminogen inhibits vascular endothelial growth factor (VEGF)-induced angiogenesis, suppresses choroidal neovascularization in mice by an inhibition of VEGF receptor-2 (VEGFR-2) specific signaling pat...
Main Authors: | Hye Cheong Koo, Yi-Yong Baek, Jun-Sup Choi, Young-Myeong Kim, Bokyung Sung, Min-Jung Kim, Jae Gyu Kim, Ji Chang You |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-04-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/8/3893 |
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