Binimetinib (MEK162) in recurrent low-grade serous ovarian cancer resistant to chemotherapy and hormonal treatment

Background: Management of advanced/recurrent low-grade serous ovarian carcinoma (LGOSC) is often challenging. Effective treatment options remain limited for hormone and chemotherapy-resistant LGSOC.CASE: A 65-year-old woman with recurrent widespread LGSOC harboring the KRAS-G12 V hotspot mutation ex...

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Bibliographic Details
Main Authors: Chanhee Han, Stefania Bellone, Luca Zammataro, Peter E. Schwartz, Alessandro D. Santin
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Gynecologic Oncology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S235257891830047X