Phenotypic variability in synthetic biology applications: dealing with noise in microbial gene expression.

The stochasticity due to the infrequent collisions among low copy-number molecules within the crowded cellular compartment is a feature of living systems. Single cell variability in gene expression within an isogenic population (i.e. biological noise) is usually described as the sum of two independe...

Full description

Bibliographic Details
Main Authors: Lucia eBandiera, Simone eFurini, Emanuele eGiordano
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00479/full