SCID/NOD mice model for 5-FU induced intestinal mucositis: Safety and effects of probiotics as therapy

Background: For chemotherapy patients, intestinal mucositis is a frequent complication. Previously, we evaluated the beneficial effect of oral probiotics in 5-Fluorouracil (5-FU) induced mucositis in BALB/c mice. Here, we used SCID/NOD mice instead to simulate the immunodeficiency of chemotherapy pa...

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Bibliographic Details
Main Authors: Lawrence Huang, Jen-Shiu Chiang Chiau, Mei-Lien Cheng, Wai-Tao Chan, Chuen-Bin Jiang, Szu-Wen Chang, Chun-Yan Yeung, Hung-Chang Lee
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Pediatrics and Neonatology
Online Access:http://www.sciencedirect.com/science/article/pii/S1875957217306824