Metallopeptidase inhibitor 1 (TIMP‐1) promotes receptor tyrosine kinase c‐Kit signaling in colorectal cancer

Metallopeptidase inhibitor 1 (TIMP‐1) promotes receptor tyrosine kinase c‐Kit signaling in colorectal cancer

Colorectal cancer (CRC) is the third most prevalent cancer worldwide causing an estimated 700 000 deaths annually. Different types of treatment are available for patients with advanced metastatic colorectal cancer, including targeted biological agents, such as cetuximab, a monoclonal antibody that t...

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Bibliographic Details
Main Authors: Cathrine Nordgaard, Sophia Doll, Ana Laura de Souza Almeida Matos, Mikkel Høeberg, Julhash Uddin Kazi, Stine Friis, Jan Stenvang, Lars Rönnstrand, Matthias Mann, José Manuel Afonso Moreira
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Molecular Oncology
Subjects:
colorectal cancer
c‐Kit
cetuximab
predictive biomarkers
omics
invasion
Online Access:https://doi.org/10.1002/1878-0261.12575

Internet

https://doi.org/10.1002/1878-0261.12575

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