Deciphering the Link Between Hyperhomocysteinemia and Ceramide Metabolism in Alzheimer-Type Neurodegeneration

Deciphering the Link Between Hyperhomocysteinemia and Ceramide Metabolism in Alzheimer-Type Neurodegeneration

Aging is one of the strongest risk factor for Alzheimer's disease (AD). However, several data suggest that dyslipidemia can either contribute or serve as co-factors in AD appearance. AD could be examined as a metabolic disorder mediated by peripheral insulin resistance. Insulin resistance is as...

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Bibliographic Details
Main Authors: Hervé Le Stunff, Julien Véret, Nadim Kassis, Jessica Denom, Kelly Meneyrol, Jean-Louis Paul, Céline Cruciani-Guglielmacci, Christophe Magnan, Nathalie Janel
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Neurology
Subjects:
NAFLD
Alzheimer's disease
hyperhomocysteinemia
sphingolipid metabolism
ceramides
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00807/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2019.00807/full

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