The Transcription Factor Zfx Regulates Peripheral T Cell Self-Renewal and Proliferation

The Transcription Factor Zfx Regulates Peripheral T Cell Self-Renewal and Proliferation

Peripheral T lymphocytes share many functional properties with hematopoietic stem cells (HSCs), including long-term maintenance, quiescence, and latent proliferative potential. In addition, peripheral T cells retain the capacity for further differentiation into a variety of subsets, much like HSCs....

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Bibliographic Details
Main Authors: Matthew R. Smith-Raska, Teresita L. Arenzana, Louise M. D’Cruz, Alireza Khodadadi-Jamayran, Aristotelis Tsirigos, Ananda W. Goldrath, Boris Reizis
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
T cell self-renewal
T cell homeostasis
homeostatic proliferation
hematopoietic stem cell
T cell stress response
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01482/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.01482/full

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