MicroRNA-101a Inhibits Cardiac Fibrosis Induced by Hypoxia via Targeting TGFβRI on Cardiac Fibroblasts

MicroRNA-101a Inhibits Cardiac Fibrosis Induced by Hypoxia via Targeting TGFβRI on Cardiac Fibroblasts

Background/Aims: Hypoxia is a basic pathological challenge that is associated with numerous cardiovascular disorders including aberrant cardiac remodeling. Transforming growth factor beta (TGF-β) signaling pathway plays a pivotal role in mediating cardiac fibroblast (CF) function and cardiac fibrosi...

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Bibliographic Details
Main Authors: Xin Zhao, Kejing Wang, Yuhua Liao, Qiutang Zeng, Yushu Li, Fen Hu, Yuzhou Liu, Kai Meng, Cheng Qian, Qing Zhang, Hongquan Guan, Kaige Feng, You Zhou, Yimei Du, Zhijian Chen
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
Cardiac fibrosis
Cardiac fibroblasts
Hypoxia
MicroRNAs
Transforming growth factor β receptor I
Online Access:http://www.karger.com/Article/FullText/369689

Internet

http://www.karger.com/Article/FullText/369689

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