Impact of immune checkpoint gene CD155 Ala67Thr and CD226 Gly307Ser polymorphisms on small cell lung cancer clinical outcome

Impact of immune checkpoint gene CD155 Ala67Thr and CD226 Gly307Ser polymorphisms on small cell lung cancer clinical outcome

Abstract This study was conducted to investigate the impact of genetic variants of immune checkpoint genes on the treatment outcome in small cell lung cancer (SCLC). In the present study, 261 platinum doublet-treated SCLC patients were enrolled. A total of 96 polymorphisms in 33 immune checkpoint-re...

Full description

Bibliographic Details
Main Authors: Jang Hyuck Lee, Seung Soo Yoo, Mi Jeong Hong, Jin Eun Choi, Soyoun Kim, Hyo-Gyoung Kang, Sook Kyung Do, Ji Hyun Kim, Sun Ah Baek, Won Kee Lee, Jae Do Yoo, Sun Ha Choi, Yong Hoon Lee, Hyewon Seo, Jaehee Lee, Shin Yup Lee, Seung Ick Cha, Chang Ho Kim, Jae Yong Park
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81260-1

Internet

https://doi.org/10.1038/s41598-021-81260-1

Similar Items