Postnatal survival of mice with maternal duplication of distal chromosome 7 induced by a Igf2/H19 imprinting control region lacking insulator function.

The misexpressed imprinted genes causing developmental failure of mouse parthenogenones are poorly defined. To obtain further insight, we investigated misexpressions that could cause the pronounced growth deficiency and death of fetuses with maternal duplication of distal chromosome (Chr) 7 (MatDup....

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Bibliographic Details
Main Authors: Li Han, Piroska E Szabó, Jeffrey R Mann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2794364?pdf=render