Histogenesis of Merkel Cell Carcinoma: A Comprehensive Review

Histogenesis of Merkel Cell Carcinoma: A Comprehensive Review

Merkel cell carcinoma (MCC) is a primary neuroendocrine carcinoma of the skin. This neoplasia features aggressive behavior, resulting in a 5-year overall survival rate of 40%. In 2008, Feng et al. identified Merkel cell polyomavirus (MCPyV) integration into the host genome as the main event leading...

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Bibliographic Details
Main Authors: Thibault Kervarrec, Mahtab Samimi, Serge Guyétant, Bhavishya Sarma, Jérémy Chéret, Emmanuelle Blanchard, Patricia Berthon, David Schrama, Roland Houben, Antoine Touzé
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Oncology
Subjects:
merkel cell polyomavirus (MCPyV)
epithelial
fibroblast
B cell
Merkel cell carcinoma (MCC)
histogenesis
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00451/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.00451/full

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