Time-dependent effect of 1,6-hexanediol on biomolecular condensates and 3D chromatin organization

Abstract Background Biomolecular condensates have been implicated in multiple cellular processes. However, the global role played by condensates in 3D chromatin organization remains unclear. At present, 1,6-hexanediol (1,6-HD) is the only available tool to globally disrupt condensates, yet the condi...

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Bibliographic Details
Main Authors: Xinyi Liu, Shaoshuai Jiang, Lin Ma, Jiale Qu, Longying Zhao, Xing Zhu, Junjun Ding
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-021-02455-3