Myc and Miz-1 have coordinate genomic functions including targeting <it>Hox </it>genes in human embryonic stem cells

<p>Abstract</p> <p>Background</p> <p>A proposed role for Myc in maintaining mouse embryonic stem (ES) cell pluripotency is transcriptional repression of key differentiation-promoting genes, but detail of the mechanism has remained an important open topic.</p> <...

Full description

Bibliographic Details
Main Authors: Varlakhanova Natalia, Cotterman Rebecca, Bradnam Keith, Korf Ian, Knoepfler Paul S
Format: Article
Language:English
Published: BMC 2011-11-01
Series:Epigenetics & Chromatin
Online Access:http://www.epigeneticsandchromatin.com/content/4/1/20