In smokers, Sonic hedgehog modulates pulmonary endothelial function through vascular endothelial growth factor

In smokers, Sonic hedgehog modulates pulmonary endothelial function through vascular endothelial growth factor

Abstract Background Tobacco-induced pulmonary vascular disease is partly driven by endothelial dysfunction. The Sonic hedgehog (SHH) pathway is involved in vascular physiology. We sought to establish whether the SHH pathway has a role in pulmonary endothelial dysfunction in smokers. Methods The ex v...

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Bibliographic Details
Main Authors: Priscilla Henno, Stanislas Grassin-Delyle, Emeline Belle, Marion Brollo, Emmanuel Naline, Edouard Sage, Philippe Devillier, Dominique Israël-Biet
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Respiratory Research
Online Access:http://link.springer.com/article/10.1186/s12931-017-0590-1

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http://link.springer.com/article/10.1186/s12931-017-0590-1

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