Polymorphisms of glucose-regulated protein 78 and risk of colorectal cancer: a case-control study in southwest China.

Glucose-regulated protein 78 (GRP78), an endoplasmic reticulum chaperone, up-regulation serves as an efficient mechanism to promote malignant transformation of colorectal cancer (CRC) and protect CRC cells against apoptosis. Recently, the analysis of GRP78 polymorphisms has already determined that G...

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Bibliographic Details
Main Authors: Dan Zhang, Bin Zhou, Yuan Li, Mojin Wang, Cun Wang, Zongguang Zhou, Xiaofeng Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3688565?pdf=render