Endothelialization of arterial vascular grafts by circulating monocytes

Acellular tissue engineered vessels functionalised with VEGF are coated with a layer of endothelial cells after in vivo implantation, but the source of the cells are unknown. Here the authors provide evidence that monocytes expressing VEGF receptors can transdifferentiate into endothelial cells via...

Full description

Bibliographic Details
Main Authors: Randall J. Smith, Bita Nasiri, Julien Kann, Donald Yergeau, Jonathan E. Bard, Daniel D. Swartz, Stelios T. Andreadis
Format: Article
Language:English
Published: Nature Publishing Group 2020-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15361-2