Characterization of an arachidonic acid-deficient (Fads1 knockout) mouse model

Arachidonic acid (20:4Δ5,8,11,14, AA)-derived eicosanoids regulate inflammation and promote cancer development. Previous studies have targeted prostaglandin enzymes in an attempt to modulate AA metabolism. However, due to safety concerns surrounding the use of pharmaceutical agents designed to targe...

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Bibliographic Details
Main Authors: Yang-Yi Fan, Jennifer M. Monk, Tim Y. Hou, Evelyn Callway, Logan Vincent, Brad Weeks, Peiying Yang, Robert S. Chapkin
Format: Article
Language:English
Published: Elsevier 2012-07-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520345053