DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis.

DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis.

The contribution of DNA methylation to the metastatic process in colorectal cancers (CRCs) is unclear.We evaluated the methylation status of 13 genes (MINT1, MINT2, MINT31, MLH1, p16, p14, TIMP3, CDH1, CDH13, THBS1, MGMT, HPP1 and ERα) by bisulfite-pyrosequencing in 79 CRCs comprising 36 CRCs withou...

Full description

Bibliographic Details
Main Authors: Kazuo Konishi, Yoshiyuki Watanabe, Lanlan Shen, Yi Guo, Ryan J Castoro, Kimie Kondo, Woonbok Chung, Saira Ahmed, Jaroslav Jelinek, Yanis A Boumber, Marcos R Estecio, Shinji Maegawa, Yutaka Kondo, Fumio Itoh, Michio Imawari, Stanley R Hamilton, Jean-Pierre J Issa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3221680?pdf=render

Internet

http://europepmc.org/articles/PMC3221680?pdf=render

Similar Items