Temporal proteomic analysis of HIV infection reveals remodelling of the host phosphoproteome by lentiviral Vif variants

Temporal proteomic analysis of HIV infection reveals remodelling of the host phosphoproteome by lentiviral Vif variants

Viruses manipulate host factors to enhance their replication and evade cellular restriction. We used multiplex tandem mass tag (TMT)-based whole cell proteomics to perform a comprehensive time course analysis of >6500 viral and cellular proteins during HIV infection. To enable specific functi...

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Bibliographic Details
Main Authors: Edward JD Greenwood, Nicholas J Matheson, Kim Wals, Dick JH van den Boomen, Robin Antrobus, James C Williamson, Paul J Lehner
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-09-01
Series:eLife
Subjects:
proteomics
HIV
Vif
PP2A
phosphorylation
lentivirus
Online Access:https://elifesciences.org/articles/18296

Internet

https://elifesciences.org/articles/18296

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