GLP-2 Attenuates LPS-Induced Inflammation in BV-2 Cells by Inhibiting ERK1/2, JNK1/2 and NF-κB Signaling Pathways

GLP-2 Attenuates LPS-Induced Inflammation in BV-2 Cells by Inhibiting ERK1/2, JNK1/2 and NF-κB Signaling Pathways

The pathogenesis of Parkinson’s disease (PD) often involves the over-activation of microglia. Over-activated microglia could produce several inflammatory mediators, which trigger excessive inflammation and ultimately cause dopaminergic neuron damage. Anti-inflammatory effects of glucagon-like peptid...

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Bibliographic Details
Main Authors: Nan Li, Bo-Wen Liu, Wen-Zhi Ren, Ju-Xiong Liu, Su-Nan Li, Shou-Peng Fu, Ya-Long Zeng, Shi-Yao Xu, Xuan Yan, Ying-Jie Gao, Dian-Feng Liu, Wei Wang
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:International Journal of Molecular Sciences
Subjects:
glucagon-like peptide-2
microglia
Parkinson’s disease
MAPK
NF-κB
Online Access:http://www.mdpi.com/1422-0067/17/2/190

Internet

http://www.mdpi.com/1422-0067/17/2/190

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