Synthesis and biological evaluation of lycorine derivatives as dual inhibitors of human acetylcholinesterase and butyrylcholinesterase
<p>Abstract</p> <p>Background</p> <p>Alzheimer’s disease (AD) is a neurologically degenerative disorder that affects more than 20 million people worldwide. The selective butyrylcholinesterase (BChE) inhibitors and bivalent cholinesterase (ChE) inhibitors represent new t...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-09-01
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Series: | Chemistry Central Journal |
Subjects: | |
Online Access: | http://journal.chemistrycentral.com/content/6/1/96 |