HIV Protease Inhibitors Sensitize Human Head and Neck Squamous Carcinoma Cells to Radiation by Activating Endoplasmic Reticulum Stress.

BACKGROUND:Human head and neck squamous cell carcinoma (HNSCC) is the sixth most malignant cancer worldwide. Despite significant advances in the delivery of treatment and surgical reconstruction, there is no significant improvement of mortality rates for this disease in the past decades. Radiotherap...

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Bibliographic Details
Main Authors: Runping Liu, Luyong Zhang, Jing Yang, Xiaoxuan Zhang, Ross Mikkelsen, Shiyu Song, Huiping Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4416809?pdf=render