CD4+CD25hiFOXP3+ cells in cord blood of neonates born from filaria infected mother are negatively associated with CD4+Tbet+ and CD4+RORγt+ T cells.

BACKGROUND:Children who have been exposed in utero to maternal filarial infection are immunologically less responsive to filarial antigens, have less pathology, and are more susceptible to acquire infection than offspring of uninfected mothers. Moreover children from filaria infected mothers have be...

Full description

Bibliographic Details
Main Authors: Ulysse Ateba-Ngoa, Ghyslain Mombo-Ngoma, Eva Zettlmeissl, Luciën E P M van der Vlugt, Sanne E de Jong, Pierre-Blaise Matsiegui, Michael Ramharter, Peter G Kremsner, Maria Yazdanbakhsh, Ayola Akim Adegnika
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4273973?pdf=render