Design of a Versatile pH-Responsive Hydrogel for Potential Oral Delivery of Gastric-Sensitive Bioactives

A pH-responsive hydrogel system was prepared by free radical polymerization of acrylamide and methyl acrylic acid in the presence of N-N′-methylene bisacrylamide. Sodium bicarbonate was further applied as a blowing agent, which afforded a porous hydrogel structure. The hydrogel system achieved a con...

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Bibliographic Details
Main Authors: Angus R. Hibbins, Pradeep Kumar, Yahya E. Choonara, Pierre P. D. Kondiah, Thashree Marimuthu, Lisa C. du Toit, Viness Pillay
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/9/10/474