Cystatin E/M suppresses legumain activity and invasion of human melanoma

<p>Abstract</p> <p>Background</p> <p>High activity of cysteine proteases such as legumain and the cathepsins have been shown to facilitate growth and invasion of a variety of tumor types. In breast cancer, several recent studies have indicated that loss of the cysteine...

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Bibliographic Details
Main Authors: Fodstad Øystein, Abrahamson Magnus, Riker Adam I, Johansen Harald T, Haugen Mads H, Briggs Jon J, Mælandsmo Gunhild M, Solberg Rigmor
Format: Article
Language:English
Published: BMC 2010-01-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/17