HDL/ApoA-1 infusion and ApoA-1 gene therapy in atherosclerosis

The HDL hypothesis stating that simply raising HDL cholesterol (HDL-C) may produce cardiovascular benefits has been questioned recently based on several randomized clinical trials using CETP inhibitors or niacin to raise HDL-C levels. However extensive pre-clinical data support the vascular protect...

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Bibliographic Details
Main Authors: Kuang-Yuh eChyu, Prediman K Shah
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Pharmacology
Subjects:
HDL
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00187/full