Novel M. tuberculosis specific IL-2 ELISpot assay discriminates adult patients with active or latent tuberculosis.

BACKGROUND:Tuberculosis (TB) still is a major worldwide health problem, with 10.4 million new cases in 2016. Only 5-15% of people infected with M. tuberculosis develop TB disease while others remain latently infected (LTBI) during their lifetime. Thus, the absence of tests able to distinguish betwee...

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Main Authors: Chiara Della Bella, Michele Spinicci, Alessia Grassi, Filippo Bartalesi, Marisa Benagiano, Katja Truthmann, Simona Tapinassi, Arianna Troilo, Sofia D'Elios, Heba Alnwaisri, Eduard Shuralev, Mahavir Singh, Alessandro Bartoloni, Mario Milco D'Elios
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5983515?pdf=render