4-Methylumbelliferone Inhibits Cancer Stem Cell Activation and Overcomes Chemoresistance in Ovarian Cancer

4-Methylumbelliferone Inhibits Cancer Stem Cell Activation and Overcomes Chemoresistance in Ovarian Cancer

We have recently shown that the extracellular matrix molecule hyaluronan (HA) plays a role in the development of ovarian cancer chemoresistance. This present study determined if HA production is increased in chemotherapy-resistant ovarian cancers and if the HA inhibitor 4-methylubelliferone (4-MU) c...

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Bibliographic Details
Main Authors: Noor A. Lokman, Zoe K. Price, Emily K. Hawkins, Anne M. Macpherson, Martin K. Oehler, Carmela Ricciardelli
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cancers
Subjects:
ovarian cancer
hyaluronan
chemotherapy resistance
cancer stem cells
4-methylumbelliferone
Online Access:https://www.mdpi.com/2072-6694/11/8/1187

Internet

https://www.mdpi.com/2072-6694/11/8/1187

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