Peroxisome proliferator-activated receptor α (PPARα) and agonist inhibit cholesterol 7α-hydroxylase gene (CYP7A1) transcription

Peroxisome proliferator-activated receptor α (PPARα) and agonist inhibit cholesterol 7α-hydroxylase gene (CYP7A1) transcription

Fibrates are widely used hypolipidemic drugs that regulate the expression of many genes involved in lipid metabolism by activating the peroxisome proliferator-activated receptor α (PPARα). The objective of this study was to investigate the mechanism of action of peroxisome proliferators and PPARα on...

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Bibliographic Details
Main Authors: Maria Marrapodi, John Y.L. Chiang
Format: Article
Language:English
Published: Elsevier 2000-04-01
Series:Journal of Lipid Research
Subjects:
bile acid synthesis
gallstones
peroxisome proliferators
hypolipidemic drugs
cytochrome P450
HNF-4
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520323981

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http://www.sciencedirect.com/science/article/pii/S0022227520323981

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