Local Acetaldehyde—An Essential Role in Alcohol-Related Upper Gastrointestinal Tract Carcinogenesis

The resident microbiome plays a key role in exposure of the upper gastrointestinal (GI) tract mucosa to acetaldehyde (ACH), a carcinogenic metabolite of ethanol. Poor oral health is a significant risk factor for oral and esophageal carcinogenesis and is characterized by a dysbiotic microbiome. Dysbi...

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Bibliographic Details
Main Authors: Mikko T. Nieminen, Mikko Salaspuro
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Cancers
Subjects:
ADH
Online Access:http://www.mdpi.com/2072-6694/10/1/11