GLP-1 improves the supportive ability of astrocytes to neurons by promoting aerobic glycolysis in Alzheimer's disease

Objective: Astrocytes actively participate in energy metabolism in the brain, and astrocytic aerobic glycolysis disorder is associated with the pathology of Alzheimer's disease (AD). GLP-1 has been shown to improve cognition in AD; however, the mechanism remains unclear. The objectives of this...

Full description

Bibliographic Details
Main Authors: Jiaping Zheng, Yunzhen Xie, Lingjia Ren, Liqin Qi, Li Wu, Xiaodong Pan, Jianxing Zhou, Zhou Chen, Libin Liu
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Molecular Metabolism
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221287782100020X