Bordetella adenylate cyclase toxin is a unique ligand of the integrin complement receptor 3
Integrins are heterodimeric cell surface adhesion and signaling receptors that are essential for metazoan existence. Some integrins contain an I-domain that is a major ligand binding site. The ligands preferentially engage the active forms of the integrins and trigger signaling cascades that alter n...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2015-12-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/10766 |