Mesenchymal stem cells decrease lung inflammation during sepsis, acting through inhibition of the MAPK pathway

Mesenchymal stem cells decrease lung inflammation during sepsis, acting through inhibition of the MAPK pathway

Abstract Background Sepsis is a severe medical condition that ranks among the top 10 causes of death worldwide and which has permanently high incidence rates. Mesenchymal stem cells (MSCs) have been found to be potent modulators of immune responses. More importantly, there is evidence that MSCs have...

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Bibliographic Details
Main Authors: Leonardo Pedrazza, Monica Cubillos-Rojas, Fernanda Cristina de Mesquita, Carolina Luft, Aline Andrea Cunha, Jose Luis Rosa, Jarbas Rodrigues de Oliveira
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Stem Cell Research & Therapy
Subjects:
Sepsis
Mitogen-activated protein kinases
Mesenchymal stem cells
Macrophages
Online Access:http://link.springer.com/article/10.1186/s13287-017-0734-8

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http://link.springer.com/article/10.1186/s13287-017-0734-8

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