An Efficient and Flexible Method for Deconvoluting Bulk RNA-Seq Data with Single-Cell RNA-Seq Data

Estimating cell type compositions for complex diseases is an important step to investigate the cellular heterogeneity for understanding disease etiology and potentially facilitate early disease diagnosis and prevention. Here, we developed a computationally statistical method, referring to Multi-Omic...

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Bibliographic Details
Main Authors: Xifang Sun, Shiquan Sun, Sheng Yang
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/10/1161