Astroglial-Mediated Remodeling of the Interhemispheric Midline Is Required for the Formation of the Corpus Callosum

Astroglial-Mediated Remodeling of the Interhemispheric Midline Is Required for the Formation of the Corpus Callosum

The corpus callosum is the major axon tract that connects and integrates neural activity between the two cerebral hemispheres. Although ∼1:4,000 children are born with developmental absence of the corpus callosum, the primary etiology of this condition remains unknown. Here, we demonstrate that midl...

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Bibliographic Details
Main Authors: Ilan Gobius, Laura Morcom, Rodrigo Suárez, Jens Bunt, Polina Bukshpun, William Reardon, William B. Dobyns, John L.R. Rubenstein, A. James Barkovich, Elliott H. Sherr, Linda J. Richards
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Cell Reports
Subjects:
astrocyte
callosal agenesis
interhemispheric fissure
Fgf8
Nfia
Nfib
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716312554

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http://www.sciencedirect.com/science/article/pii/S2211124716312554

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