3D assessment of intervertebral disc degeneration in zebrafish identifies changes in bone density that prime disc disease

Abstract Back pain is a common condition with a high social impact and represents a global health burden. Intervertebral disc disease (IVDD) is one of the major causes of back pain; no therapeutics are currently available to reverse this disease. The impact of bone mineral density (BMD) on IVDD has...

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Bibliographic Details
Main Authors: Erika Kague, Francesco Turci, Elis Newman, Yushi Yang, Kate Robson Brown, Mona S. Aglan, Ghada A. Otaify, Samia A. Temtamy, Victor L. Ruiz-Perez, Stephen Cross, C. Patrick Royall, P. Eckhard Witten, Chrissy L. Hammond
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-021-00156-y