Recent Progress in CFTR Interactome Mapping and Its Importance for Cystic Fibrosis

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) is a chloride channel found in secretory epithelia with a plethora of known interacting proteins. Mutations in the CFTR gene cause cystic fibrosis (CF), a disease that leads to progressive respiratory illness and other complications of pheno...

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Bibliographic Details
Main Authors: Sang Hyun Lim, Elizabeth-Ann Legere, Jamie Snider, Igor Stagljar
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00997/full