Conformational Analysis of Misfolded Protein Aggregation by FRET and Live-Cell Imaging Techniques

Cellular homeostasis is maintained by several types of protein machinery, including molecular chaperones and proteolysis systems. Dysregulation of the proteome disrupts homeostasis in cells, tissues, and the organism as a whole, and has been hypothesized to cause neurodegenerative disorders, includi...

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Bibliographic Details
Main Authors: Akira Kitamura, Kazuhiro Nagata, Masataka Kinjo
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:International Journal of Molecular Sciences
Subjects:
FCS
Online Access:http://www.mdpi.com/1422-0067/16/3/6076