Improved Immune Responses Against Zika Virus After Sequential Dengue and Zika Virus Infection in Humans

Improved Immune Responses Against Zika Virus After Sequential Dengue and Zika Virus Infection in Humans

The high levels of dengue-virus (DENV) seroprevalence in areas where the Zika virus (ZIKV) is circulating and the cross-reactivity between these two viruses have raised concerns on the risk of increased ZIKV disease severity for patients with a history of previous DENV infections. To determine the r...

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Bibliographic Details
Main Authors: Félix G. Delgado, Karina I. Torres, Jaime E. Castellanos, Consuelo Romero-Sánchez, Etienne Simon-Lorière, Anavaj Sakuntabhai, Claude Roth
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Viruses
Subjects:
dengue virus
zika virus
T-cell epitopes
cross-reactive T cells
immunodominance
neutralizing antibodies
antibody-dependent-enhancement (ADE)
Online Access:http://www.mdpi.com/1999-4915/10/9/480

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http://www.mdpi.com/1999-4915/10/9/480

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