Lithium Inhibits GSK3β and Augments GluN2A Receptor Expression in the Prefrontal Cortex

Glycogen synthase kinase 3β (GSK3β) is a highly conserved serine/threonine kinase that has been implicated in both psychiatric and neurodegenerative diseases including schizophrenia, bipolar disorder, and Alzheimer's disease; therefore regulating its activity has become an important strategy fo...

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Bibliographic Details
Main Authors: Sarah A. Monaco, Brielle R. Ferguson, Wen-Jun Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2018.00016/full