Prognostic Significance of Gene Expression and DNA Methylation Markers in Circulating Tumor Cells and Paired Plasma Derived Exosomes in Metastatic Castration Resistant Prostate Cancer

Prognostic Significance of Gene Expression and DNA Methylation Markers in Circulating Tumor Cells and Paired Plasma Derived Exosomes in Metastatic Castration Resistant Prostate Cancer

Liquid biopsy, based on the analysis of circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA), provides non-invasive real-time monitoring of tumor evolution and therapeutic efficacy. We performed for the first time a direct comparison study on gene expression and DNA methylation markers i...

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Bibliographic Details
Main Authors: Martha Zavridou, Areti Strati, Evangelos Bournakis, Stavroula Smilkou, Victoria Tserpeli, Evi Lianidou
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
prostate cancer
liquid biopsy
CTCs
extracellular vesicles
exosomes
DNA methylation
Online Access:https://www.mdpi.com/2072-6694/13/4/780

Internet

https://www.mdpi.com/2072-6694/13/4/780

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