Treatment of bisphosphonate-related osteonecrosis using platelet-rich plasma: microtomographic, microscopic, and immunohistochemical analyses

Abstract The present study aimed to investigate the use of platelet-rich plasma (PRP) on tooth extraction sites in rats treated with bisphosphonates. Thirty Albinus Wistar male rats were administered 0.035 mg/kg zoledronic acid intravenously for 8 weeks, divided into four administrations with a 2-we...

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Main Authors: Camila Lopes CARDOSO, Cláudia CURRA, Marcos Martins CURI, Mariza Akemi MATSUMOTO, Camila Dionísio ARGENTINO, Solange de Oliveira Braga FRANZOLIN, Dulce CONSTANTINO, Daniela Nicolielo BARBOSA, Osny FERREIRA JÚNIOR
Format: Article
Language:English
Published: Sociedade Brasileira de Pesquisa Odontológica
Series:Brazilian Oral Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242019000100242&lng=en&tlng=en