The RNA‐binding protein MEX3A is a prognostic factor and regulator of resistance to gemcitabine in pancreatic ductal adenocarcinoma

The RNA‐binding protein MEX3A is a prognostic factor and regulator of resistance to gemcitabine in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer. Most patients present with advanced disease at diagnosis, which only permits palliative chemotherapeutic treatments. RNA dysregulation is a hallmark of most human cancers, including PDAC. To test the impact of RNA processing dysr...

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Bibliographic Details
Main Authors: Valentina Panzeri, Isabella Manni, Alessia Capone, Chiara Naro, Andrea Sacconi, Silvia Di Agostino, Luisa deLatouliere, Andrea Montori, Emanuela Pilozzi, Giulia Piaggio, Gabriele Capurso, Claudio Sette
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:Molecular Oncology
Subjects:
cell cycle
chemoresistance
PDAC
RNA‐binding proteins
RNA metabolism
Online Access:https://doi.org/10.1002/1878-0261.12847

Internet

https://doi.org/10.1002/1878-0261.12847

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