CD146, a novel target of CD44-signaling, suppresses breast tumor cell invasion

CD146, a novel target of CD44-signaling, suppresses breast tumor cell invasion

Abstract Background We have previously validated three novel CD44-downstream positively regulated transcriptional targets, including Cortactin, Survivin and TGF-β2, and further characterized the players underlying their separate signaling pathways. In the present study, we identified CD146 as a pote...

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Bibliographic Details
Main Authors: Allal Ouhtit, Mohammed E. Abdraboh, Andrew D. Hollenbach, Hatem Zayed, Madhwa H. G. Raj
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Cell Communication and Signaling
Subjects:
CD146
CD44
Breast cancer
Metastasis
MMPs
Online Access:http://link.springer.com/article/10.1186/s12964-017-0200-3

Internet

http://link.springer.com/article/10.1186/s12964-017-0200-3

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