Suppressed OGT expression inhibits cell proliferation while inducing cell apoptosis in bladder cancer

Suppressed OGT expression inhibits cell proliferation while inducing cell apoptosis in bladder cancer

Abstract Background This study aimed to explore hyper-O-linked N-acetylglucosaminylation (O-GlcNAcylation) with an elevation of the expression of O-linked-β-N-acetylglucosamine transferase (OGT) in human bladder cancer. Methods Immunohistochemical staining for OGT and O-GlcNAcylation was performed i...

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Bibliographic Details
Main Authors: Longsheng Wang, Shaojun Chen, Ziwei Zhang, Junfeng Zhang, Shiyu Mao, Jiayi Zheng, Yang Xuan, Mengnan Liu, Keke Cai, Wentao Zhang, Yadong Guo, Wei Zhai, Xudong Yao
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Cancer
Subjects:
Autophagy
Bladder cancer
DNA damage response
O-GlcNAcylation
Online Access:http://link.springer.com/article/10.1186/s12885-018-5033-y

Internet

http://link.springer.com/article/10.1186/s12885-018-5033-y

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